#Autoimmunity

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Tom Kindlon"Research finds potential “molecular mimics” behind <a href="https://disabled.social/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID</a> -induced <a href="https://disabled.social/tags/autoimmune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmune</a> disease"<a href="https://www.eurekalert.org/news-releases/1078341" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.eurekalert.org/news-releases/1078341</a>“some of the human proteins the researchers identified as likely targets of COVID-induced <a href="https://disabled.social/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> are only found in people with specific genetics”Hashtags: <a href="https://a.gup.pe/u/longcovid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@longcovid</a> <a href="https://disabled.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#LongCovid</a> <a href="https://disabled.social/tags/PASC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PASC</a> <a href="https://disabled.social/tags/PwLC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PwLC</a> <a href="https://disabled.social/tags/postcovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postcovid</a> <a href="https://disabled.social/tags/postcovid19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postcovid19</a> <a href="https://disabled.social/tags/Covidlonghaulers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Covidlonghaulers</a> <a href="https://disabled.social/tags/PostCovidSyndrome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PostCovidSyndrome</a> <a href="https://a.gup.pe/u/covid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@covid19</a> <a href="https://disabled.social/tags/Coronavirus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Coronavirus</a> <a href="https://disabled.social/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID19</a> <a href="https://disabled.social/tags/COVID_19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID_19</a> <a href="https://disabled.social/tags/COVID%E3%83%BC19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVIDー19</a> <a href="https://disabled.social/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SARSCoV2</a> <a href="https://chirp.social/@novid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@novid@chirp.social</a> <a href="https://disabled.social/tags/novid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#novid</a> <a href="https://a.gup.pe/u/novid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@novid@a.gup.pe</a> <a href="https://disabled.social/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CovidIsNotOver</a> <a href="https://a.gup.pe/u/auscovid19" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@auscovid19</a> <a href="https://disabled.social/tags/auscovid19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#auscovid19</a>

Science Updates"...if you can figure out how a rare disease mutation is working, you learn something about the normal proteins that all of us have," noted Dr Jonathan Miner, MD, PhD.Insights into a rare disease known as SAVI have put a spotlight on a major immune trigger.<a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#immunology</a> <a href="https://mastodon.social/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> <a href="https://mastodon.social/tags/disease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#disease</a> <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicine</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://www.labroots.com/trending/cell-and-molecular-biology/28740/key-trigger-immune-overactivity-identified" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.labroots.com/trending/cell-and-molecular-biology/28740/key-trigger-immune-overactivity-identified</a>

David UsharauliInitially, the thymus was believed to be an endocrine organ because its removal in early life caused changes in the ovaries and testes. Now, we understand these changes were linked to autoimmunity. 🤔🔬💡 <a href="https://bookstodon.com/tags/thymus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#thymus</a> <a href="https://bookstodon.com/tags/Tregs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tregs</a> <a href="https://bookstodon.com/tags/endocrine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocrine</a> <a href="https://bookstodon.com/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> <a href="https://bookstodon.com/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://bookstodon.com/tags/history" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#history</a>

David Usharauli10/ So, antigen-specific autoimmunity can't happen under the prevailing Treg biology model. ❌ But then, how do antigen-specific autoimmune diseases occur? 🤔 Here’s the twist… 🔄 <a href="https://bookstodon.com/tags/Microbiota" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Microbiota</a> <a href="https://bookstodon.com/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a>

David Usharauli7/ But how could we lose a self-antigen? Not realistic. And if a self-antigen is lost, how can autoimmunity occur? No antigen, no autoimmunity. 🚫 <a href="https://bookstodon.com/tags/SelfAntigen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SelfAntigen</a> <a href="https://bookstodon.com/tags/Tregs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tregs</a> <a href="https://bookstodon.com/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a>

David Usharauli9/ If the lost anchor antigen is similar to the target self-antigen, Treg–IL-2+ T cell collaboration stays intact. 🔄 If they’re different, losing the anchor antigen shouldn’t affect other self-antigens. ⚖️ No disruption → No autoimmunity! <a href="https://bookstodon.com/tags/Tregs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tregs</a> <a href="https://bookstodon.com/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a>

David Usharauli5/ But what antigens do Tregs and other T cells recognize to collaborate on IL-2 supply? Is it auto-antigen? Unlikely. Why? Because for autoimmunity to happen, Tregs would need to lose their functionality. ⚠️ <a href="https://bookstodon.com/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://bookstodon.com/tags/Tregs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tregs</a>

Science Updates"The diagnostic toolkits that we use today don't make much use of the immune system's internal record..." said Maxim Zaslavsky, PhD. "But our immune system is constantly surveilling our bodies with B & T cells, which act like molecular threat sensors. Combining information from the two main arms of the immune system gives us a more complete picture of the immune system's response to <a href="https://mastodon.social/tags/disease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#disease</a> & the pathways to <a href="https://mastodon.social/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> & <a href="https://mastodon.social/tags/vaccine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vaccine</a> response." <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://www.labroots.com/trending/clinical-and-molecular-dx/28633/machine-learning-immune-biomarkers-diagnose-disease" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.labroots.com/trending/clinical-and-molecular-dx/28633/machine-learning-immune-biomarkers-diagnose-disease</a>

Jennifer Moore 😷New test aimed at identifying different types of Long Covid."of those tested 60% showed a poor quantity & quality of antibodies... "... a hyper immune response to the infection for 15%... which means their bodies produced too many antibodies..."The remaining 25% had an unclear response"Interesting. I'd already said I thought LC was an umbrella term, & that mine was primarily immune system over-reaction.<a href="https://www.bbc.co.uk/news/articles/c4g7722wxj4o" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.bbc.co.uk/news/articles/c4g7722wxj4o</a><a href="https://scicomm.xyz/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#LongCovid</a> <a href="https://scicomm.xyz/tags/testing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#testing</a> <a href="https://scicomm.xyz/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a>

Tom KindlonFrom ME Research UKA systematic review – published in BMC Immunology, has investigated existing evidence on the role of autoimmunity in ME/CFS. Read a summary of the review and findings here: bit.ly/3VWf4lh <a href="https://disabled.social/tags/MECFS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MECFS</a> <a href="https://disabled.social/tags/AutoImmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AutoImmunity</a> <a href="https://a.gup.pe/u/mecfs" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@mecfs</a>

Science Updates"An aging thymus leads to a 'leaky' immune system," said senior study author John White, a Professor and Chair at McGill University. "This means the thymus becomes less effective at filtering out immune cells that could mistakenly attack healthy tissues, increasing the risk of autoimmune diseases like type 1 diabetes."<a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicine</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biology</a> <a href="https://mastodon.social/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> <a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#immunology</a> <a href="https://www.labroots.com/trending/cell-and-molecular-biology/27980/vitamin-deficiency-raise-autoimmune-disease-risk" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.labroots.com/trending/cell-and-molecular-biology/27980/vitamin-deficiency-raise-autoimmune-disease-risk</a>

IT NewsUsing Donor Immune Cells to Mass-Produce CAR-T Autoimmune Therapies - As exciting as immunotherapies are in terms of fighting cancer, correcting autoimm... - <a href="https://hackaday.com/2024/10/07/using-donor-immune-cells-to-mass-produce-car-t-autoimmune-therapies/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://hackaday.com/2024/10/07/using-donor-immune-cells-to-mass-produce-car-t-autoimmune-therapies/</a> <a href="https://schleuss.online/tags/autoimmunedisease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunedisease</a> <a href="https://schleuss.online/tags/cart" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cart</a>-celltherapy <a href="https://schleuss.online/tags/medicalhacks" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicalhacks</a> <a href="https://schleuss.online/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a>

Thiago Carvalho'To elucidate the in vivo function of neoself-antigens presented on MHC-II by decreased Ii expression, we analyzed the antigen specificity of clonally expanded autoreactive T cells in SLE patients as well as in drug-inducible Ii knockout (Ii-iKO) mice, which allowed us to delete the Ii from adult mice. We demonstrate that neoself-antigens presented on MHC-II upon decreases in Ii expression levels are recognized by CD4+ T cells as non-self-antigens and are the primary targets for autoreactive T cells clonally expanded in SLE patients. Furthermore, we suggested that EBV reactivation, which downregulates Ii expression, could be involved in the activation of neoself-reactive T cells.' <a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://www.sciencedirect.com/science/article/abs/pii/S0092867424009139" rel="nofollow noopener noreferrer" target="_blank">https://www.sciencedirect.com/science/article/abs/pii/S0092867424009139</a>

Thiago Carvalho'The T-cell engager teclistamab acts on T cells through CD3 (the defining marker of T cells) and targets plasmablasts and plasma cells through BCMA. Teclistamab has been shown to be highly effective in patients with multiple myeloma.4 Thus, we hypothesized that teclistamab may be effective for targeting severe autoimmune diseases, even after failure of conventional B-cell depletion.' <a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunotherapy</a> <a href="https://qoto.org/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://www.nejm.org/doi/full/10.1056/NEJMc2408786" rel="nofollow noopener noreferrer" target="_blank">https://www.nejm.org/doi/full/10.1056/NEJMc2408786</a>

Charité BerlinImpressive case at <a href="https://wisskomm.social/tags/Charit%C3%A9Berlin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CharitéBerlin</a>: In a 23-year-old female patient with severe systemic <a href="https://wisskomm.social/tags/lupus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lupus</a> erythematosus, the <a href="https://wisskomm.social/tags/AutoimmuneDisease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AutoimmuneDisease</a> is no longer detectable after treatment with a cancer medication. Only time will tell if the results will last, but the case marks the starting point for further studies.👉 <a href="https://www.charite.de/en/service/press_reports/artikel/detail/impressive_results_against_autoimmune_disease/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.charite.de/en/service/press_reports/artikel/detail/impressive_results_against_autoimmune_disease/</a><a href="https://wisskomm.social/tags/Medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medicine</a> <a href="https://wisskomm.social/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a> <a href="https://wisskomm.social/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Research</a> <a href="https://wisskomm.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ScienceMastodon</a> <a href="https://wisskomm.social/tags/MedMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedMastodon</a> <a href="https://wisskomm.social/tags/Medibubble" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medibubble</a> <a href="https://wisskomm.social/tags/SLE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SLE</a> <a href="https://wisskomm.social/tags/Charit%C3%A9Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CharitéImmunology</a> <a href="https://wisskomm.social/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a>

halama_immuno<a href="https://qoto.org/@cyrilpedia" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@cyrilpedia</a> Together with the organ-specific composition of the <a href="https://mstdn.science/tags/innateimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#innateimmunity</a> cellular mix, there is still a vast landscape that needs our attention. Why does the dynamic of <a href="https://mstdn.science/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> or <a href="https://mstdn.science/tags/antitumoral" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antitumoral</a> show such a great organ-specific diversity...? And not only on the T cell repertoire... <a href="https://med-mastodon.com/@gpollara" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@gpollara</a> <a href="https://mstdn.science/@scholpp_lab" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@scholpp_lab</a>

Chuck DarwinWhen researchers gave healthy mice antibodies from patients with <a href="https://c.im/tags/Long" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Long</a> <a href="https://c.im/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID</a>, some of the animals began showing Long COVID symptoms —specifically heightened pain sensitivity and dizziness. It is among the first studies to offer enticing evidence for the <a href="https://c.im/tags/autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#autoimmunity</a> <a href="https://c.im/tags/hypothesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hypothesis</a>. The research was led by <a href="https://c.im/tags/Akiko" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Akiko</a> <a href="https://c.im/tags/Iwasaki" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Iwasaki</a>, PhD, Sterling Professor of Immunobiology at Yale School of Medicine (YSM). “We believe this is a big step forward in trying to understand and provide treatment to patients with this subset of Long COVID,” Iwasaki said. Iwasaki zeroed in on autoimmunity in this study for several reasons. First, Long COVID’s persistent nature suggested that a chronic triggering of the immune system might be at play. Second, women between ages 30 and 50, who are most susceptible to autoimmune diseases, are also at a heightened risk for Long COVID. Finally, some of Iwasaki’s previous research had detected heightened levels of antibodies in people infected with SARS-CoV-2.<a href="https://www.yalemedicine.org/news/antibodies-from-long-covid-patients-provide-clues-to-autoimmunity-hypothesis" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.yalemedicine.org/news/antibodies-from-long-covid-patients-provide-clues-to-autoimmunity-hypothesis</a>

Thiago Carvalho'We discovered high-titer neutralizing autoantibodies against interleukin-10 in a child with infantile-onset inflammatory bowel disease (IBD), a phenocopy of inborn errors of interleukin-10 signaling.' <a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2312302" rel="nofollow noopener noreferrer" target="_blank">https://www.nejm.org/doi/full/10.1056/NEJMoa2312302</a>

Thiago Carvalho'Twenty-nine different Car-T treatments for autoimmune diseases, ranging from the muscle inflammation condition myositis to multiple sclerosis, are now being tested in clinical trials by drugmakers including Novartis and Bristol Myers Squibb'<a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://qoto.org/tags/CARTcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CARTcells</a> <a href="https://www.ft.com/content/a974f4c1-bb8a-4a1b-9d88-a2cf14be5c6e" rel="nofollow noopener noreferrer" target="_blank">https://www.ft.com/content/a974f4c1-bb8a-4a1b-9d88-a2cf14be5c6e</a>

Thiago CarvalhoCART cells & Lupus'But the prize money may help make future relapses less likely. Radic plans to use it to figure out how an interaction between cells called trogocytosis affects CAR-T therapy success, according to a press release about the award. Meanwhile, Schett will use his reward to analyze the extent of B cell depletion in the lymph nodes of people with lupus who were treated with CAR-T, a step towards optimizing disease management.' <a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunotherapy</a> <a href="https://qoto.org/tags/Autoimmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Autoimmunity</a> <a href="https://qoto.org/tags/Lupus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Lupus</a> <a href="https://www.fiercebiotech.com/research/insight-prize-winners-researchers" rel="nofollow noopener noreferrer" target="_blank">https://www.fiercebiotech.com/research/insight-prize-winners-researchers</a>

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